RAB3D IS CRITICAL FOR SECRETORY GRANULE MATURATION IN PC12 CELLS.

Rab3D is critical for secretory granule maturation in PC12 cells.

Neuropeptide- and hormone-containing secretory granules (SGs) are synthesized at the trans-Golgi network (TGN) as immature secretory granules (ISGs) and complete their maturation in the F-actin-rich cell cortex.This maturation process is characterized by acidification-dependent processing of cargo proteins, condensation of the SG matrix Neoprene Gl

read more

Altered frontocingulate activation during aversive interoceptive processing in young adults transitioning to problem stimulant use

Problems associated with stimulant use have been linked to frontocingulate, insular, and thalamic dysfunction during decision-making and alterations in interoceptive Clothing processing.However, little is known about how interoception and decision-making interact and contribute to dysfunctions that promote the transition from recreational drug use

read more

Elephantiasis and Directed Occupational Rehabilitation

The aim of the present study was to demonstrate the cure of elephantiasis over Round Dish a ten-year follow-up period and novel discoveries with directed occupational rehabilitation.A 66-year-old female patient with a history of bilateral lower limb lymphedema reported the aggravation of the condition over the years, reaching stage III (elephantias

read more